같이 로타바이러스에 대해 공부해요!

로타바이러스, 어떻게 예방하죠?

  • 로타바이러스란?
  • 로타바이러스
    위장관염의 증상
  • 로타바이러스 감염 예방법
  • 백신잘알 테스트

우리 아이 백신 접종 어디까지 알고 있나요?

로타텍과 함께하는 백신잘알 TEST
References
  • 질병관리청, 예방접종도우미>예방접종관리>예방접종 알아보기> 예방접종 주의사항 및 금기사항, Available at https://nip.cdc.go.kr/irgd/index.html
  • 질병관리청, 예방접종대상 감염병의 역학과 관리 제5판, 충북, 2017
  • 질병관리청, 어린이 표준예방접종 일정표, 2020
  • Shim JO, Thai Than V, Ryoo E, et al. Distribution of rotavirus G and P genotypes approximately two years following the introduction of rotavirus vaccines in South Korea. J Med Virol. 2013;85(7):1307-12
  • 대한소아과학회, 예방접종지침서 제9판, 2018
  • Payne DC, et al. Long-term Consistency in Rotavirus Vaccine Protection: RV5 and RV1 Vaccine Effectiveness in US Children, 2012-2013.
    Clin Infect Dis. 2015; 61: 1792-9
  • 질병관리청, 로타바이러스 감염증 발생 증가 예방수칙 준수 당부 보도자료_2018.2
  • Raebel MA, Ou BS. et al. Rotavirus disease and prevention in infants and children. Pharmacotherapy. 1999;19:1279-95.
  • 로타텍 허가사항, 식품의약품안전처.
  • Banyai K et al. Systematic review of regional and temporal trends in global rotavirus strain diversity in the pre rotavirus vaccine era: Insights for understanding the impact of rotavirus vaccination programs. Vaccine. 2012;30S:A122-A130
  • Jeong et al Rotavirus infection PUBLIC HEALTH WEEKLY REPORT, CDC 2016: 931:611
  • Tate et al. Global, Regional, and National Estimates of Rotavirus Mortality in Children <5 Years of Age, 2000-2013. CID 2016:62 (Suppl 2); 596-5105
  • WHO. Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19). 16-24 Feb. 2020. Available at <https://www.who.int/docs/default-source/coronaviruse/who-china-joint-mission-on-covid-19-final-report.pdf> Accessed Aug. 14, 2020.
  • Pitzer VE, et al. Direct and Indirect Effects of Rotavirus Vaccination: Comparing Predictions from Transmission Dynamic Models.
    PLoS One. 2012:7(8):e42320.

Study design
  • We searched PubMed using the keyword “rotavirus to identify studies that met each of the following criteria: data collection midpoint in year 1998 or later, study period of a 12-month increment, and detection of rotavirus infection by enzyme immunoassay in at least 100 children <5 years of age who were hospitalized with diarrhea and systematically enrolled through active surveillance.
    We also included data from countries that participated in the World Health Organization (WHO)-coordinated rotavirus surveillance network between 2008 and 2013 that met these criteria, To predict the proportion of diarrhea due to rotavirus, we constructed a multiple linear regression model. To determine the number of rotavirus deaths in children <5 years of age from 2000 to 2013, we multiplied annual, country-specific estimates of the proportion of diarrhea due to rotavirus from the regression model by the annual number of WHO-estimated child deaths caused by diarrhea in each country
  • 745 stool samples were collected from children under the age of 5 years. 745 children were hospitalized for acute gastroenteritis in three university hospitals located in Seoul, Incheon, and Gangwon provinces from Mar 2008 to Feb 2010. Genotyping of human rotaviruses was performed on 299 rotavirus-positive samples obtained from 745 stool samples.

Study result

b. G genotype은 G1 (51.5%), G3 (24.0%), G4 (15.4%), G9 (6.4%), G2 (4.7%)순으로 나타났고, P genotypes은 P[8](72.6%), P[6] (19.1%), P[4] (6.0%) 순으로 나타났습니다.4

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